Dragon Pharma Cardio Daily Rx

Natural Cardiovascular Support

Heart Health

• Helps to Maintain Healthy Blood Pressure Ɨ
• Promotes Healthy Anti-Inflammatory Response Ɨ
• Supports Endothelial Health Ɨ

Literally every single second of every single day, your heart works non-stop. Critically vital to our very existence, the heart is the single most important organ for sustaining life and the amount of wear and tear on it through our lifetime is nothing to take lightly.

Dragon Pharma Cardio Daily Rx was formulated to help you maintain a healthy cardiovascular system, using research supported ingredients to support healthy blood pressure, healthy blood flow, a natural anti-inflammatory response and the overall maintenance of healthy endothelial tissue. Ɨ

Cardio Daily Rx Ingredients

Pine Bark Extract

Naturally high in Procyanidin compounds which are chain-like structures consisting of catechins similar those found in green tea

Suggested in research to improve blood flow via increased nitric oxide production; Exerts a cardioprotective effect1

Modest decreases in blood pressure have been observed in various research studies with additional research ongoing2

Exhibited to cause increases in plasma antioxidant capacity and alters the plasma lipoprotein profile by lowering LDL cholesterol3

Celery Seed Extract

Believed to help mitigate sodium retention by acting as a natural diuretic; Specifically helpful in the circulatory system, aiding in regulating blood pressure and the release of excess fluid around the heart5

Grape Seed Extract

Derived from the seeds of common grapes, they are a rich source of procyanidin molecules (up to 81% of the content)6

Procyanidins (specifically from grape seed) have been demonstrated to exert anti-oxidant effects in regard to neuroprotection7

Undergoing further human studies, it has been observed to have a significant spike in nitric oxide levels via stimulation of the enzyme that increases nitric oxide production8

It has been found in various studies to lower heart rate resulting in decreased systolic blood pressure and overall blood pressure management9

Olive Leaf Extract

Natural supplement derived from the leaves of the olive plant; High in the bioactives oleuropein and ligstroside

Shown to provide positive effects including reduced blood pressure; Effective in both managing and preventing hypertension10

Aids in improved endothelial function via increasing the production of nitric oxide that aids in the relaxation of blood vessels11

Shown to reduce the production of molecules that contribute to plaque damage and also reduce platelet aggregation12

Can prevent the oxidation of LDL cholesterol which is one of the biggest contributors to atherosclerosis13

Ubiquinol

Ubiquinol is the active form of CoQ10 and is used in the body to promote cellular energy production, especially in high-energy demand organs such as heart, brain and liver14

Provides potent antioxidant support to reduce oxidative stress and free radicals15

Can promote and maintain a healthy heart and cardiovascular system and maintain healthy LDL cholesterol levels16

AstraGin®

Amplifies the absorption of ingredients including peptides, amino acids, fatty acids, vitamins, and phytonutrients by up-regulating the absorption specific mRNA and transporters17

Shown to rejuvenate ulcerated and damaged intestinal walls and reduce intestinal submucosa inflammation18

Supports digestive system by maintaining a healthy microbiota population via mending ulcerated and damaged intestinal epithelial cell surfaces for the microbiota to populate19

Helps support stronger immune functions by mending ulcerated epithelial cells and reducing the inflammation in intestines18

Cardio Daily Rx References

1. Nishioka K. Pycnogenol, French maritime pine bark extract, augments endothelium-dependent vasodilation in humans. J Hypertens Res. 2007;30(9):775-780. doi:10.1291/hypres.30.775
2. Zhang Z. Effect of Pycnogenol Supplementation on Blood Pressure: A Systematic Review and Meta-analysis. Iran J Public Health. 2018;47(6):779-787.
3. Devaraj S. Supplementation with a pine bark extract rich in polyphenols increases plasma antioxidant capacity and alters the plasma lipoprotein profile. Lipids J. 2002;37(10):931-934. doi:10.1007/s11745-006-0982-3
4. El-Shinnawy N. The therapeutic applications of celery oil seed extract on the plasticizer di(2-ethylhexyl) phthalate toxicity. J Toxicol Ind Health. 2015;31(4):355-366. doi:10.1177/0748233713475515
5. Moghadam M. Antihypertensive Effect of Celery Seed on Rat Blood Pressure in Chronic Administration. J Med Food. 2013;16(6):558-563. doi:10.1089/jmf.2012.2664
6. Yilmazer-Musa M. Grape seed and tea extracts and catechin 3-gallates are potent inhibitors of α-amylase and α-glucosidase activity. J Agric Food Chem. 2012;60(36):8924-8929. doi:10.1021/jf301147n
7. Kim Y. Antioxidant and cytoprotective effects of oligomeric and polymeric procyanidin fractions from defatted grape seed in PC12 cells. J Med Food. 2012;15(5):490-494. doi:10.1089/jmf.2011.1963
8. Shao Z. Grape seed proanthocyanidins protect cardiomyocytes from ischemia and reperfusion injury via Akt-NOS signaling. J Cell Biochem. 2009;107(4):697-705. doi:10.1002/jcb.22170
9. Zhang H. The impact of grape seed extract treatment on blood pressure changes. Medicine (Baltimore). 2016;95(33):e4247. doi:10.1097/MD.0000000000004247
10. Somova L. Antihypertensive, antiatherosclerotic and antioxidant activity of triterpenoids isolated from Olea europaea, subspecies africana leaves. J Ethnopharmacol. 2003;84(2-3):299-305. doi:10.1016/s0378-8741(02)00332-x
11. Visioli F. Oleuropein, the bitter principle of olives, enhances nitric oxide production by mouse macrophages. LIfe Sci. 1998;62(6):541-546. doi:10.1016/s0024-3205(97)01150-8
12. Scoditti E. Mediterranean diet polyphenols reduce inflammatory angiogenesis through MMP-9 and COX-2 inhibition in human vascular endothelial cells: a potentially protective mechanism in atherosclerotic vascular disease and cancer. Arch Biochem Biophys. 2012;527(2):81-89. doi:10.1016/j.abb.2012.05.003
13. Visioli F. Oleuropein protects low density lipoprotein from oxidation. Life Sci. 1994;55(24):1965-1971. doi:10.1016/0024-3205(94)00529-x
14. Saini R. Coenzyme Q10: The essential nutrient. J Pharm Bioallied Sci. 2011;3(3):466-467.
15. Littaru GP. Bioenergetic and antioxidant properties of coenzyme Q10: recent developments. J Mol Biotechnol. 2007;37(1):31-37. doi:10.1007/s12033-007-0052-y
16. Allen R. Coenzyme Q10 Increases Cholesterol Efflux and Inhibits Atherosclerosis through microRNAs. Arterioscler Thromb Vasc Biol. 2014;34(9):1795-1797. doi:10.1161/ATVBAHA.114.303741
17. Chang T. Effect of ginsenosides on glucose uptake in human Caco-2 cells is mediated through altered Na+/glucose cotransporter 1 expression. J Agric Food Chem. 2007;55(5):1993-1998. doi:10.1021/jf062714k
18. Lee S. Astragaloside II promotes intestinal epithelial repair by enhancing L-arginine uptake and activating the mTOR pathway. Sci Rep. 2017;7(1). doi:10.1038/s41598-017-12435-y
19. Wang H. Bioactivity enhancement of herbal supplements by intestinal microbiota focusing on ginsenosides. Am J Chin Med. 2011;39(6):1103-1115. doi:10.1142/S0192415X11009433

CARDIO Daily Rx Directions:

As a dietary supplement, take 1 serving (2 capsules) daily with a meal.