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In a pharmacokinetic comparison study, lysine butyrate (BIOMEnd™) showed a Cmax over 5x greater and an AUC 1.75x higher than tributyrin, with a significantly faster Tmax (20 min vs. 51.5 min) (La Monica et al., 2025). These metrics reflect superior systemic uptake and faster biological action, making BIOMEnd™ ideal for applications targeting the gut-brain axis, energy, and mood regulation.
Synbiotics can also seem to reduce Colonic transit time (CTT), increase defecation frequency, and improve stool consistency, with some additional middling evidence on constipation as well. Paired with the pre- and postbiotics in Gut Glory, one can expect an increase in all of the above symptoms.





